Non-invasive Vascular Screening Device
Registration Number: 20182210170, Production Certificate: 20162890
- Applicable scope: it is applicable for measuring blood pressure, Arterial Velocity Pulse Index (AVI), Arterial Pressure Volume Index (API), Central Systolic Blood Pressure (CSBP, estimated value) and Central Aortic Pulse Pressure (CAPP, estimated value). The values are only for diagnostic reference.
- The value of blood pressure measured by the device is equivalent to that picked up by the auscultatory method, and the error rate conforms to the requirements specified in YY 0667-2008.
- The device has passed clinical verification according to the requirements in YY 0670-2008, and its safety and effectiveness has been proved to conform to the related regulations in YY 0670-2008.
- The device should be used under the direction of a physician.
How To Use AVE-2000 Pro Arteriosclerosis Test Device?
Please download the user’s manual PDF file here:
Terminology
Blood Pressure
The blood pressure is the pressure of the flowing blood against the vascular wall, and it also serves as the force to propel the blood flowing in the vessels.
Pulse Rate
The frequency of arterial pulse wave detected by the cuff, which is generally comparable to heart rate except under some special situations, such as in subjects with arrhythmia or severe occlusive disease in artery or cardiac valve.
AVI & API
AVI & API are the new vascular index jointly researched and developed by RIKEN, AIST, and Shisei Datum in Japan.
AVI & API are subject to the effect of age, gender, cholesterol level, blood pressure as the well as the history of diabetes, smoking and exercise, etc.
AVI may be reduced through regular exercise.
AVI is a new vascular index that developed jointly by Shisei Datum in Japan and RIKEN.
Himeno Ryutaro with his sub generation integration simulation team, and Gao muzhou with his dominant organ Scale study team, are the research and development teams of RIKEN. Gao muzhou is also a professor of Tokyo University.
Principle: AVI shows the characteristics of the pulse waveform when the cuff pressure is higher than maximum blood pressure, and meanwhile converts them into numerical values as the indices of the central arterial stiffness. The higher the value is, the higher risk of arterial stiffness it represents.
The upper waveforms of below graph are those of cuff pressure pulse wave, and the lower ones are the differentiated waveforms (differentiated pulse wave). The shape of the cuff oscillation wave varies with the increase and early arrival of reflected pressure waves accompanying aging or arterial stiffening, presenting an enhanced pressure augmentation in late systole followed by a
steeper pressure decrease. AVI is an index used to quantitatively assess such wave changes, which is calculated based on the ratio of the valley value (Vr) to the peak value (Vf) of the time-differentiated cuff wave (AVI=(Vr/Vf)×20).
API is a new vascular index that developed jointly by AIST and Shisei Datum in Japan.
Principle: The more elastic the arteries are, the more drastic the arterial volume changes when the cuff pressure decreases. The blood vessel stiffness is converted into numerical values using the gradient of the curve as an index. The higher the value is, the higher risk of upper-arm arterial stiffness it represents. The cuff pressure-artery volume curve is firstly measured by a cuff with a decreasing working pressure, then the curve is fitted with an arctan function (A*arctan(B*X+C)+D). Finally, API is defined as the reciprocal of coefficient B (API=1/B).